Comprehensive Use of Cardiopulmonary Exercise Testing Identifies Adults with Congenital Heart Disease at Increased Mortality Risk in the Medium Term Running title: Inunzuka et al.; Exercise testing in congenital heart disease

Exercise Physiology Comprehensive Use of Cardiopulmonary Exercise Testing Identifies Adults With Congenital Heart Disease at Increased Mortality Risk in the Medium Term

Background—Parameters of cardiopulmonary exercise testing were recently identified as strong predictors of mortality in adults with congenital heart disease. We hypothesized that combinations of cardiopulmonary exercise testing parameters may provide optimal prognostic information on midterm survival in this population. Methods and Results—A total of 1375 consecutive adult patients with congeni...

Comprehensive use of cardiopulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term.

BACKGROUND Parameters of cardiopulmonary exercise testing were recently identified as strong predictors of mortality in adults with congenital heart disease. We hypothesized that combinations of cardiopulmonary exercise testing parameters may provide optimal prognostic information on midterm survival in this population. METHODS AND RESULTS A total of 1375 consecutive adult patients with conge...

Cardiopulmonary Exercise Testing in Adults with Congenital Heart Disease: Can We Prognosticate and Improve Prognosis? Running title: Rhodes; Exercise testing in congenital heart disease

Cardiopulmonary exercise testing in adults with congenital heart disease.

Adults with congenital heart disease (CHD) are at high risk for morbidity and mortality. Identifying those who are at highest risk of complications can be challenging, in part because self-reported functional status is not a reliable indicator of physiological status. Individuals with CHD may present with exercise limitation due to a variety of cardiac and non-cardiac causes. Cardiopulmonary ex...

Asymmetrical Dimethylarginine - More Sensitive than NT-proBNP to Diagnose Heart Failure in Adults with Congenital Heart Disease

BACKGROUND Chronic heart failure is an important cause for morbidity and mortality in adults with congenital heart disease (ACHD). While NT-proBNP is an established biomarker for heart failure of non-congenital origin, its value in ACHD has limitations. Asymmetrical dimethylarginine (ADMA) correlates with disease severity and independently predicts adverse clinical events in heart failure of no...